Download HIV and AIDS: Basic Elements and Priorities by S. Kartikeyan, R.N. Bharmal, R.P. Tiwari, P.S. Bisen PDF

By S. Kartikeyan, R.N. Bharmal, R.P. Tiwari, P.S. Bisen

In June 1981, the facilities for disorder keep watch over and Prevention mentioned the 1st proof of a brand new affliction that may later turn into often called got Immunodeficiency Syndrome (AIDS). HIV and AIDS: easy parts and Priorities is a concise number of all features of this ailment, and is a resource of available wisdom. All at the moment encouraged preventive measures similar to health and wellbeing schooling, condom use, more secure intercourse practices, and therapy of sexually transmitted infections were included. the major parts of this quantity are: - up to date info on a number of dimensions of the HIV/AIDS epidemic, - discusses new anti retroviral treatment / medicines, new medicines less than medical trials and preventive HIV vaccine, - covers present moral, felony and social concerns concerning HIV/AIDS, - evaluates basic public knowledge approximately HIV/AIDS, - encompasses a worldwide point of view and data approximately HIV/AIDS. This quantity is a superb reference for technological know-how graduates and put up graduates, scientific scholars, study students and scientists the world over.

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Sample text

On activation by foreign antigens, they differentiate and proliferate with the help of IL-2, which is secreted by T4 cells. T8 cells also produce an antiviral cytokine, called CD8 cell-produced antiviral factor (CAF), which directly inhibits the replication of HIV in T4 cells, without causing their lysis. Killer T-cells are cytotoxic cells that bear CD8 co-receptors. They can recognise foreign antigens in association with MHC Class I. These cells proliferate and differentiate in response to IL-2 secreted by T-helper cells.

They are capable of recognising foreign antigens in association with MHC Class II. On activation by foreign antigens, they secrete chemicals called “cytokines”. There are about 40 different types of cytokines, which have overlapping effects. Interleukin-2 (IL-2) is a cytokine, which is responsible for proliferation of T-cells. IL-4, also a cytokine, increases production of antibodies by B-cells. T4 (or CD4) cells are required for optimal production of antibodies by B-cells and for cytotoxic action of T8 cells.

Thus, T4 cells “help” the action of other lymphocytes. Suppressor cells (also called “T8”, or “CD8 T-lymphocytes”) comprise 20–30 per cent of the T-lymphocytes in the peripheral blood. They bear CD8 receptors on their surfaces. These cells suppress immunoglobulin synthesis and act as a brake on immune response. On activation by foreign antigens, they differentiate and proliferate with the help of IL-2, which is secreted by T4 cells. T8 cells also produce an antiviral cytokine, called CD8 cell-produced antiviral factor (CAF), which directly inhibits the replication of HIV in T4 cells, without causing their lysis.

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